Commentary: Use fusion to avoid confusion

Histocompatibility: Clarifying Fusion Confusion

In the colonial tunicate Botryllus schlosseri, a co-dominant trait determines the capacity of adjacent colonies to fuse or reject. An innovative RNA sequencing approach has now identified the gene that predicts the outcomes of this naturally occurring allograft.

How to avoid pitfalls in antibody use

Antibody use is ubiquitous in the biomedical sciences. However, determining best research practices has not been trivial. Many commercially available antibodies and antibody-conjugates are poorly characterized and lack proper validation. Uncritical application of such useless tools has contributed to the reproducibility crisis in biomedical research. Despite early initiatives such as MIAPAR or ...

Use Complexity to Avoid Vote Manipulation

Aggregating the preferences of self-interested agents is a key problem for multiagent systems. A common method for doing so is to vote over the candidates. Unfortunately, the Gibbard-Satterthwaite’s theorem shows that when there are more than three candidates, every nondictorial voting scheme for choosing the winning candidate is manipulable (in other words, there exist situations so that some ...

To Use or Avoid Global Clocks ?

Definitions of outcome, response and effect in imaging research to avoid confusion.

The % change of normalized percent atheroma volume (PAV) is shown in the upper left panel and of total atheroma volume (TAV) in the upper right panel. The comparison is between segments with endothelial dysfunction and those with normal endothelial function. Representative examples of intravascular ultrasound (IVUS) findings are shown in the lower panel. Segments with endothelial dysfunction sh...